Publications (all)
Publikationen Tissue Biology Research Unit
(aus ZORA Zurich Open Repository and Archive)
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Publications
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Safety and efficacy of bio-engineered, autologous dermo-epidermal skin grafts in adolescent and adult burn patients: 1-year results of a prospective, randomized, controlled, multicenter phase IIB clinical trial EClinicalMedicine, 90, 103665. https://doi.org/10.1016/j.eclinm.2025.103665
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Long-term outcomes of a cultured autologous dermo-epidermal skin substitute in children: 5 year results of a phase I clinical trial Journal of Burn Care & Research, 46(2):326-334.
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The influence of CD26+ and CD26− fibroblasts on the regeneration of human dermo-epidermal skin substitutes Scientific Reports, 12:1944.
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Bioprinting and plastic compression of large pigmented and vascularized human dermo-epidermal skin substitutes by means of a new robotic platform Journal of Tissue Engineering, 13:204173142210885.
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Detrusor bioengineering using a cell-enriched compressed collagen hydrogel Journal of Biomedical Materials Research. Part B, 108(7):3045-3055.
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Bioengineering of Fetal Skin: Differentiation of Amniotic Fluid Stem Cells into Keratinocytes Fetal Diagnosis and Therapy, 47(3):198-204.
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Bioengineering and in utero transplantation of fetal skin in the sheep model: A crucial step towards clinical application in human fetal spina bifida repair Journal of Tissue Engineering and Regenerative Medicine, 14(1):58-65.
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Bio-engineering of fetal cartilage for in utero spina bifida repair Pediatric Surgery International, 36(1):25-31.
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A cultured autologous dermo-epidermal skin substitute for full-thickness skin defects: a phase I, open, prospective clinical Trial in children Plastic and Reconstructive Surgery, 144(1):188-198.
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A simplified fabrication technique for cellularized high-collagen dermal equivalents Biomedical Materials, 14(4):041001.
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Impact of human mesenchymal cells of different body site origins on the maturation of dermo-epidermal skin substitutes Pediatric Surgery International, 35(1):121-127.
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Induction of angiogenic and inflammation-associated dermal biomarkers following acute UVB exposure on bio-engineered pigmented dermo-epidermal skin substitutes in vivo Pediatric Surgery International, 35(1):129-136.
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Epithelial proliferation in inflammatory skin disease is regulated by tetratricopeptide repeat domain 7 (Ttc7) in fibroblasts and lymphocytes Journal of Allergy and Clinical Immunology, 143(1):292-304.e8.
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Genome editing of human primary keratinocytes by CRISPR/Cas9 reveals an essential role of the NLRP1 inflammasome in UVB sensing Journal of Investigative Dermatology, 138(12):2644-2652.
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Expression of inflammasome proteins and inflammasome activation occurs in human, but not in murine keratinocytes Cell Death and Disease, 9(2):24.
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UVB exposure of a humanized skin model reveals unexpected dynamic of keratinocyte proliferation and Wnt inhibitor balancing Journal of Tissue Engineering and Regenerative Medicine, 12(2):505-515.
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Characterization of M1 and M2 polarization of macrophages in vascularized human dermo-epidermal skin substitutes in vivo Pediatric Surgery International, 34(2):129-135.
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The expression pattern of keratin 24 in tissue-engineered dermo-epidermal human skin substitutes in an in vivo model Pediatric Surgery International, 34(2):237-244.
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The low affinity neurotrophin receptor CD271 regulates phenotype switching in melanoma Nature Communications, 8(1):1988.
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Human adipose mesenchymal cells inhibit melanocyte differentiation and the pigmentation of human skin via increased expression of TGF-β1 Journal of Investigative Dermatology, 137(12):2560-2569.
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Comparison of in vivo immune responses following transplantation of vascularized and non-vascularized human dermo-epidermal skin substitutes Pediatric Surgery International, 33(3):377-382.
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The effect of wound dressings on a bio-engineered human dermo-epidermal skin substitute in a rat model Journal of Burn Care & Research, 38(6):354-364.
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Factors affecting the mechanical behavior of collagen hydrogels for skin tissue engineering Journal of the Mechanical Behavior of Biomedical Materials, 69:85-97.
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Successful grafting of tissue-engineered fetal skin Pediatric Surgery International, 32(12):1177-1182.
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Myelinated and unmyelinated nerve fibers reinnervate tissue-engineered dermo-epidermal human skin analogs in an in vivo model Pediatric Surgery International, 32(12):1183-1191.
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About ATMPs, SOPs and GMP: the hurdles to produce novel skin grafts for clinical use Transfusion Medicine and Hemotherapy, 43(5):344-352.
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Functional Analysis of Vascularized Collagen/Fibrin Templates by MRI In Vivo Tissue engineering. Part C, Methods, 22(8):747-755.
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Visualisation of newly synthesised collagen in vitro and in vivo Scientific Reports, 6:18780.
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Collagen hydrogels strengthened by biodegradable meshes are a basis for dermo-epidermal skin grafts intended to reconstitute human skin in a one-step surgical intervention Journal of Tissue Engineering and Regenerative Medicine, 10(1):81-91.
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Characterization of vasculogenic potential of human adipose-derived endothelial cells in a three-dimensional vascularized skin substitute Pediatric Surgery International, 32(1):17-27.
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The influence of stromal cells on the pigmentation of tissue-engineered dermo-epidermal skin grafts Tissue Engineering. Part A, 21(5-6):960-969.
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Long-term expression pattern of melanocyte markers in light- and dark-pigmented dermo-epidermal cultured human skin substitutes Pediatric Surgery International, 31(1):69-76.
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Characterization of pigmented dermo-epidermal skin substitutes in a long-term in vivo assay Experimental Dermatology, 24(1):16-21.
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Experimental tissue engineering of fetal skin Pediatric Surgery International, 30(12):1241-1247.
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Differential expression of granulocyte, macrophage, and hypoxia markers during early and late wound healing stages following transplantation of tissue-engineered skin substitutes of human origin Pediatric Surgery International, 30(12):1257-1264.
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Tissue-engineered dermo-epidermal skin grafts prevascularized with adipose-derived cells Biomaterials, 35(19):5065-5078.
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Analysis of blood and lymph vascularization patterns in tissue-engineered human dermo-epidermal skin analogs of different pigmentation Pediatric Surgery International, 30(2):223-231.
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Tissue-engineered dermo-epidermal skin analogs exhibit de novo formation of a near natural neurovascular link 10 weeks after transplantation Pediatric Surgery International, 30(2):165-172.
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Bioengineering dermo-epidermal skin grafts with blood and lymphatic capillaries Science Translational Medicine, 6(221):221ra14.
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De novo epidermal regeneration using human eccrine sweat gland cells: Higher competence of secretory over absorptive cells Journal of Investigative Dermatology, 134(6):1735-1742.
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Tissue engineering of skin: human tonsil-derived mesenchymal cells can function as dermal fibroblasts Pediatric Surgery International, 30(2):213-222.
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Tissue engineering of skin for wound coverage European Journal of Pediatric Surgery, 23(05):375-382.
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Human amniotic fluid derived cells can competently substitute dermal fibroblasts in a tissue-engineered dermo-epidermal skin analog Pediatric Surgery International, 29(1):61-69.
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Optimizing in vitro culture conditions leads to a significantly shorter production time of human dermo-epidermal skin substitutes Pediatric Surgery International, 29(3):249-256.
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"Trooping the color": restoring the original donor skin color by addition of melanocytes to bioengineered skin analogs Pediatric Surgery International, 29(3):239-247.
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Human eccrine sweat gland cells turn into melanin-uptaking Keratinocytes in dermo-epidermal skin substitutes Journal of Investigative Dermatology, 133(2):316-324.
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A new model for preclinical testing of dermal substitutes for human skin reconstruction Pediatric Surgery International, 29(5):479-488.
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Rebuild, restore, reinnervate: do human tissue engineered dermo-epidermal skin analogs attract host nerve fibers for innervation? Pediatric Surgery International, 29(1):71-78.
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Glucose sensing in human epidermis using mid-infrared photoacoustic detection Biomedical Optics Express, 3(4):667-680.
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Modified plastic compression of collagen hydrogels provides an ideal matrix for clinically applicable skin substitutes Tissue engineering. Part C, 18(6):464-474.
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Matriderm(®) 1 mm versus Integra(®) Single Layer 1.3 mm for one-step closure of full thickness skin defects: a comparative experimental study in rats. Pediatric Surgery International, 28(2):171-177.
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Engineering melanoma progression in a humanized environment in vivo Journal of Investigative Dermatology, 132(1):144-153.
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Novel treatment for massive lower extremity avulsion injuries in children: slow, but effective with good cosmesis European Journal of Pediatric Surgery, 21(2):106-110.
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Determining the origin of cells in tissue engineered skin substitutes: a pilot study employing in situ hybridization Pediatric Surgery International, 27(3):255-261.
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Osmotic expanders in children: no filling - no control - no problem? European Journal of Pediatric Surgery, 21(3):163-167.
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Skingineering II: transplantation of large-scale laboratory-grown skin analogues in a new pig model Pediatric Surgery International, 27(3):249-254.
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Skingineering I: engineering porcine dermo-epidermal skin analogues for autologous transplantation in a large animal model Pediatric Surgery International, 27(3):241-247.
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Tissue engineering of skin Burns, 36(4):450-460.
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Human eccrine sweat gland cells can reconstitute a stratified epidermis Journal of Investigative Dermatology, 130(8):1996-2009.
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Transglutaminases, involucrin, and loricrin as markers of epidermal differentiation in skin substitutes derived from human sweat gland cells Pediatric Surgery International, 26(1):71-77.
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Formation of human capillaries in vitro: The engineering of prevascularized matrices Tissue Engineering. Part A, 16(1):269-282.
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Markers to evaluate the quality and self-renewing potential of engineered human skin substitutes in vitro and after transplantation Journal of Investigative Dermatology, 129(2):480-490.
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Matriderm versus Integra: a comparative experimental study Burns, 35(1):51-57.
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Impact of carbon dioxide versus air pneumoperitoneum on peritoneal cell migration and cell fate Surgical Endoscopy, 20(10):1607-1613.