Dissemination CRPP

Induction of angiogenic and inflammation-associated dermal biomarkers following acute UVB exposure on bio-engineered pigmented dermo-epidermal skin substitutes in vivo

Pediatric Surgery International, 35(1):129-136.

Micka-Michalak, Katarzyna ; Biedermann, Thomas ; Reichmann, Ernst ; Meuli, Martin ; Klar, Agnes S (2019

Characterization of M1 and M2 polarization of macrophages in vascularized human dermo-epidermal skin substitutes in vivo.

Pediatric Surgery International, 34(2):129-135.

Klar, Agnes S ; Michalak-Mićka, Katarzyna ; Biedermann, Thomas ; Simmen-Meuli, Claudia ; Reichmann, Ernst ; Meuli, Martin (2018).

The expression pattern of keratin 24 in tissue-engineered dermo-epidermal human skin substitutes in an in vivo model

Pediatric Surgery International, 34(2):237-244.Klar, Agnes S ; Michalak, Katarzyna ; Böttcher-Haberzeth, Sophie ; Reichmann, Ernst ; Meuli, Martin ; Biedermann, Thomas (2018).

Impact of human mesenchymal cells of different body site origins on the maturation of dermo-epidermal skin substitutes

Pediatric Surgery International, 35(1):121-127.

Michalak-Micka, Katarzyna ; Klar, Agnes S ; Böttcher-Haberzeth, Sophie ; Reichmann, Ernst ; Meuli, Martin ; Biedermann, Thomas (2019).

Human adipose mesenchymal cells inhibit melanocyte differentiation and the pigmentation of human skin via increased expression of TGF-β1

J Invest Dermatol. 2017 Jul 31. pii: S0022-202X(17)32732-X. doi: 10.1016/j.jid.2017.06.027. [Epub ahead of print]

Klar AS, Biedermann T, Michalak K, Michalczyk T, Meuli-Simmen C, Scherberich A, Meuli M, Reichmann E

UVB exposure of a humanized skin model reveals unexpected dynamic of keratinocyte proliferation and Wnt inhibitor balancing

J Tissue Eng Regen Med. 2017 Jul 17. doi: 10.1002/term.2519. [Epub ahead of print]

Michalczyk T, Biedermann T, Böttcher-Haberzeth S, Klar AS, Meuli M, Reichmann E

Comparison of in vivo immune responses following transplantation of vascularized and non-vascularized human dermo-epidermal skin substitutes

Pediatr Surg Int. 2017 Mar;33(3):377-382. doi: 10.1007/s00383-016-4031-x. Epub 2016 Dec 20.

Klar AS, Biedermann T, Simmen-Meuli C, Reichmann E, Meuli M

Human adipose mesenchymal cells inhibit melanocyte differentiation and the pigmentation of human skin via increased expression of TGF-β1

Journal of Investigative Dermatology; JID-2017-0039

A.S. Klar, T. Biedermann, K. Michalak, T. Michalczyk, C. Meuli-Simmen, A. Scherberich, M. Meuli, E. Reichmann

About ATMPs, SOPs and GMP: the hurdles to produce novel skin grafts for clinical use

Transfusion Medicine and Hemotherapy, 43(5):344-352.

Hartmann-Fritsch, Fabienne; Marino, Daniela; Reichmann, Ernst

Myelinated and unmyelinated nerve fibers reinnervate tissue-engineered dermo-epidermal human skin analogs in an in vivo model

Pediatric Surgery International, 32(12):1183-1191.

Biedermann, T; Klar, A S; Böttcher-Haberzeth, S; Reichmann, E; Meuli, M

Successful grafting of tissue-engineered fetal skin

Pediatric Surgery International; December 2016, Volume 32, Issue 12, pp 1177–1182

L. Mazzone, M. Pratsinis, L. Pontiggia, E. Reichmann, M. Meuli

Characterization of vasculogenic potential of human adipose-derived endothelial cells in a three-dimensional vascularized skin substitute.

Pediatric Surgery International, 32(1):17-27.

Klar, Agnes S; Güven, Sinan; Zimoch, Jakub; Zapiórkowska, Natalia A; Biedermann, Thomas; Böttcher-Haberzeth, Sophie; Meuli-Simmen, Claudia; Martin, Ivan; Scherberich, Arnaud; Reichmann, Ernst; Meuli, Martin

Collagen hydrogels strengthened by biodegradable meshes are a basis for dermo-epidermal skin grafts intended to reconstitute human skin in a one-step surgical intervention

Journal of Tissue Engineering and Regenerative Medicine, 10(1):81-91.

Hartmann-Fritsch, Fabienne; Biedermann, Thomas; Braziulis, Erik; Luginbühl, Joachim; Pontiggia, Luca; Böttcher-Haberzeth, Sophie; van Kuppevelt, Toin H; Faraj, Kaeuis A; Schiestl, Clemens; Meuli, Martin; Reichmann, Ernst

The influence of stromal cells on the pigmentation of tissue-engineered dermo-epidermal skin grafts

Tissue Eng Part A. 2015 Mar;21(5-6):960-9. doi: 10.1089/ten.TEA.2014.0327. Epub 2015 Jan 7

Biedermann, Thomas; Böttcher-Haberzeth, Sophie; Klar, Agnieszka S; Widmer, Daniel S; Pontiggia, Luca; Weber, Andreas D; Weber, Daniel M; Schiestl, Clemens; Meuli, Martin; Reichmann

Characterization of pigmented dermo-epidermal skin substitutes in a long-term in vivo assay

Exp Dermatol. 2015 Jan;24(1):16-21. doi: 10.1111/exd.12570

Böttcher-Haberzeth, Sophie; Biedermann, Thomas; Klar, Agnieszka S; Widmer, Daniel S; Neuhaus, Kathrin; Schiestl, Clemens; Meuli, Martin; Reichmann, Ernst

Tissue-engineered dermo-epidermal skin grafts prevascularized with adipose-derived cells.

Biomaterials. 2014 Jun;35(19):5065-78. doi: 10.1016/j.biomaterials.2014.02.049. Epub 2014 Mar 27.

Klar AS1, Güven S2, Biedermann T1, Luginbühl J1, Böttcher-Haberzeth S1, Meuli-Simmen C3, Meuli M4, Martin I2, Scherberich A5, Reichmann E6.

Long-term expression pattern of melanocyte markers in light- and dark-pigmented dermo-epidermal cultured human skin substitutes.

Pediatr Surg Int. 2015 Jan;31(1):69-76. doi: 10.1007/s00383-014-3622-7. Epub 2014 Oct 18

Biedermann T1, Klar AS, Böttcher-Haberzeth S, Michalczyk T, Schiestl C, Reichmann E, Meuli M.

Differential expression of granulocyte, macrophage, and hypoxia markers during early and late wound healing stages following transplantation of tissue-engineered skin substitutes of human origin.

Pediatr Surg Int. 2014 Oct 18. [Epub ahead of print]

Klar AS1, Böttcher-Haberzeth S, Biedermann T, Michalak K, Kisiel M, Reichmann E, Meuli M.

De novo Epidermal Regeneration Using Human Eccrine Sweat Gland Cells: Higher Competence of Secretory Over Absorptive Cells.

J Invest Dermatol. 2014 Jan 21. doi: 10.1038/jid.2014.30.

Pontiggia L, Biedermann T, Böttcher-Haberzeth S, Oliveira C, Braziulis E, Klar A, Meuli-Simmen C, Meuli M, Reichmann E.

Bioengineering dermo-epidermal skin grafts with blood and lymphatic capillaries.

Sci Transl Med. 2014 Jan 29;6(221):221ra14. doi: 10.1126/scitranslmed.3006894.

Marino D, Luginbühl J, Scola S, Meuli M, Reichmann E.

Tissue-engineered dermo-epidermal skin analogs exhibit de novo formation of a near natural neurovascular link 10 weeks after transplantation.

Pediatr Surg Int. 2014 Feb;30(2):165-72. doi: 10.1007/s00383-013-3446-x.

Biedermann T, Klar AS, Böttcher-Haberzeth S, Schiestl C, Reichmann E, Meuli M.

Tissue engineering of skin: human tonsil-derived mesenchymal cells can function as dermal fibroblasts.

Pediatr Surg Int. 2014 Feb;30(2):213-22. doi: 10.1007/s00383-013-3454-x.

Böttcher-Haberzeth S, Biedermann T, Klar AS, Pontiggia L, Rac J, Nadal D, Schiestl C, Reichmann E, Meuli M.

Analysis of blood and lymph vascularization patterns in tissue-engineered human dermo-epidermal skin analogs of different pigmentation.

Pediatr Surg Int. 2014 Feb;30(2):223-31. doi: 10.1007/s00383-013-3451-0.

Klar AS, Böttcher-Haberzeth S, Biedermann T, Schiestl C, Reichmann E, Meuli M.

Tissue Engineering of Skin for Wound Coverage

Eur J Pediatr Surg. 2013 Oct;23(5):375-82. doi: 10.1055/s-0033-1352529.

Epub 2013 Aug 27

Biedermann T, Böttcher-Haberzeth S, Reichmann E.